Semax

Semax is a synthetic heptapeptide analog of ACTH(4–10) with the sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). Preclinical research investigates Semax in experimental models involving neurotrophic signaling, cognitive function, neural injury, aging, and inflammatory responses.

The peptide is supplied as a lyophilized powder with ≥99% HPLC purity and has a defined molecular profile, including CAS number 80714-61-0, molecular formula C37H51N9O10S, and molar mass 813.93 g/mol.

What is Semax?

Semax is a synthetic seven-amino-acid peptide based on the ACTH(4–10) sequence. Its research profile is primarily associated with experimental neuroscience, particularly studies examining neurotrophic signaling and cellular responses in neural tissue.

The supplied sequence is:

Met-Glu-His-Phe-Pro-Gly-Pro

Semax is also described as an ACTH(4–10) analog and by the sequence abbreviation MEHFPGP.

Preclinical studies have explored Semax in models of cognitive function, brain injury, aging, neurodegeneration, and inflammatory processes. These findings represent experimental research and should not be interpreted as established therapeutic effects in humans.

Semax specifications

Product detail	Specification
Product	Semax
CAS Number	80714-61-0
Molecular formula	C37H51N9O10S
Molar mass	813.93 g/mol
Sequence	Met-Glu-His-Phe-Pro-Gly-Pro
Length	7 amino acids
Synonyms	Semax; ACTH(4–10) analog; MEHFPGP
Purity	≥99% (HPLC)
Form	Lyophilized powder
Long-term storage	−20°C (−4°F)
Reconstituted storage	2–8°C (36–46°F)
Reconstitution solvent	Bacteriostatic water for laboratory use
Intended use	Laboratory research only

What is Semax studied for?

Semax is primarily investigated in preclinical neuroscience and neurobiology research.

Neurotrophic-factor research

One area of interest is the relationship between Semax and neurotrophic signaling. Experimental studies have examined pathways involving factors such as BDNF and NGF, particularly in models of neural stress or injury.

Cognitive research

Semax has been investigated in experimental models involving learning, memory, and cognitive performance, including research related to aging and stress.

Brain-injury research

Preclinical studies have explored Semax in models involving stroke and other forms of neural injury, examining cellular responses and mechanisms associated with neural adaptation and recovery.

Neurodegeneration research

Experimental work has investigated the peptide in models relevant to neurodegenerative processes, including pathways associated with cellular survival and apoptosis.

Inflammatory research

Semax has also been studied in relation to inflammatory signaling and adaptive cellular responses in experimental neural models.

These research areas are preclinical and do not establish Semax as a treatment for stroke, brain injury, neurodegenerative disease, cognitive impairment, or other medical conditions.

What makes Semax different?

Semax has a clearly defined seven-amino-acid structure derived from the ACTH(4–10) peptide region.

Its sequence, Met-Glu-His-Phe-Pro-Gly-Pro, provides a straightforward molecular identifier for laboratory research. The supplied material is additionally specified by CAS number 80714-61-0, molecular formula C37H51N9O10S, and molar mass 813.93 g/mol.

Its research profile is particularly centered on neurotrophic and neural-response pathways, distinguishing it from peptides primarily investigated for peripheral tissue, metabolic, or endocrine applications.

Why consider this Semax research peptide?

When evaluating Semax peptide for sale, researchers should prioritize verifiable molecular and analytical information over broad claims about cognitive enhancement or neurological performance.

This material is specified at ≥99% HPLC purity and supplied in lyophilized form. The product information identifies its sequence, CAS number, molecular formula, molar mass, and storage requirements.

For laboratories comparing Semax materials, these specifications provide a practical framework for determining whether the product corresponds to the intended ACTH(4–10) analog.

Storage and handling

The supplied specifications indicate −20°C (−4°F) for long-term storage and 2–8°C (36–46°F) after reconstitution.

Bacteriostatic water for laboratory use is listed as the reconstitution solvent.

Researchers should follow the applicable product documentation and laboratory procedures when preparing, storing, and handling Semax. Specific preparation conditions should be determined by the requirements of the research protocol.

Frequently asked questions

What is Semax?

Semax is a synthetic seven-amino-acid analog of ACTH(4–10) studied in preclinical research involving neurotrophic signaling, cognitive models, neural injury, aging, and inflammatory pathways.

What is the sequence of Semax?

The sequence is Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP).

How many amino acids are in Semax?

Semax contains seven amino acids, making it a heptapeptide.

What is Semax studied for?

Preclinical research investigates Semax in areas including neurotrophic-factor signaling, cognitive function, brain-injury models, neurodegenerative research, and inflammatory responses.

What is the relationship between Semax and ACTH?

Semax is a synthetic ACTH(4–10) analog. Its seven-amino-acid sequence is Met-Glu-His-Phe-Pro-Gly-Pro.

What is the CAS number for Semax?

The listed CAS number is 80714-61-0.

What is the molecular formula of Semax?

The supplied molecular formula is C37H51N9O10S.

What is the molar mass of Semax?

The listed molar mass is 813.93 g/mol.

What is the purity of Semax?

The specified purity is ≥99% by HPLC.

What form is Semax supplied in?

Semax is supplied as a lyophilized powder.

How should Semax be stored?

The supplied specifications list −20°C (−4°F) for long-term storage and 2–8°C (36–46°F) after reconstitution.

What is used to reconstitute Semax?

The supplied product information lists bacteriostatic water for laboratory use as the reconstitution solvent.

Is Semax intended for human use?

No. This product is intended for laboratory research only and is not for human or veterinary consumption.